Developed in 1912, MDMA was reclassified in 1985 as a Schedule I substance, a drug defined as having no accepted medical use and a high potential for abuse.
Preliminary numbers show a nearly 4 percent decrease in deaths from opioids, largely fentanyl, but a rise in deaths from meth and cocaine.
ยฉ Erin Schaff/The New York Times
Empty cartridges of Kloxxado, a naloxone nasal spray that is twice as concentrated as Narcan, lay on the street after being used to revive a man in Portland, Ore., last year.